Is this SDS the latest revision?

This Safety Data Sheet was issued by Sigma-Aldrich Ireland Ltd on 26 February 2023 under GHS/CLP. ISDSS syncs its database regularly to keep documents current.

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Can I use this SDS as my COSHH risk assessment?

No. An SDS provides the hazard information you need, but a COSHH assessment must consider how the substance is actually used in your workplace. The matching Chemical Risk Assessment (CRA) on this page is a starting point you should adapt to your own tasks and controls.

Safety Data SheetChemical Risk Assessment

Temozolomide

by Sigma-Aldrich Ireland Ltd

SDS · PDF, approx. 220 KB CRA · PDF, approx. 180 KB

Temozolomide is supplied by Sigma-Aldrich Ireland Ltd under product code 5.00609. This page provides both the Safety Data Sheet (SDS) and the Chemical Risk Assessment (CRA) for this substance, under GHS/CLP regulations for UK workplace use under COSHH. The full SDS and CRA documents are available to download above.

This SDS was last revised on 26 February 2023. The matching CRA is updated in line with SDS revisions. Workplaces handling this substance should retain a current SDS and risk assessment for the duration of use.

Language: English
Regulation: GHS/CLP
Revision Date: 26 Feb 2023
Signal Word: DANGER
Product Code: 5.00609
CAS Number: 85622-93-1

Switch between the Safety Data Sheet and the Chemical Risk Assessment for this substance.

Hazards at a GlanceFrom the Safety Data Sheet

Signal Word: DANGER

GHS07Harmful / irritant

GHS08Health hazard

Hazard Statements (H-phrases)

H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H340: May cause genetic defects.
H350: May cause cancer.
H360FD: See full Safety Data Sheet for the hazard statement wording.
H335: May cause respiratory irritation.

Need the full hazard breakdown? Precautionary statements, first aid, physical properties and exposure controls are in the full SDS PDF.

Common QuestionsAbout this Safety Data Sheet

Chemical Risk Assessment SummaryFrom the Chemical Risk Assessment

Assessment Summary

This Chemical Risk Assessment is derived from the Safety Data Sheet for Temozolomide issued by Sigma-Aldrich Ireland Ltd on 26 February 2023 It presents the substance's hazards organised by risk level, with the relevant regulatory statements and recommended controls for each. These hazards are rated across three levels: High, Medium and Low Risk, based on the hazard classifications in the SDS.

Hazard PreviewA snapshot of substance hazards and controls

Rating Before Controls

HIGH RISK

H340: May cause genetic defects

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and un-derstood

P281 Use personal protective equipment as required

P501 Dispose of contents/container to correct disposal area.

P405 Store locked up.

P308 + P313 IF exposed or concerned: Get medical advice/attention.

Rating Before Controls

HIGH RISK

H350: May cause cancer

P201 Obtain special instructions before use

P202 Do not handle until all safety precautions have been read and un-derstood.

P281 Use personal protective equipment as required.

P501 Dispose of contents/container to correct disposal area.

P405 Store locked up

P308 + P313 IF exposed or concerned: Get medical advice/attention.

Rating Before Controls

HIGH RISK

H319: Causes serious eye irritation

P264 Wash skin thoroughly after handling.

P280: Wear protective gloves/protective clothing/eye protection/face protection.

P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P313 + P337 If eye irritation persists Get medical advice/attention

Note: This is a preview of the substance's hazards. A substance commonly carries more hazards. Download the full Chemical Risk Assessment for more information.

Recommended Control MeasuresKey PPE and handling controls

Need to download the Chemical Risk Assessment? The full CRA PDF includes all hazard classifications, regulatory statements and recommended controls.

Common QuestionsAbout this Risk Assessment

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Temozolomide

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