Is this SDS the latest revision?

This Safety Data Sheet was issued by Cayman Chemical Co. on 24 October 2025 under OSHA. ISDSS syncs its database regularly to keep documents current.

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Can I use this SDS as my COSHH risk assessment?

No. An SDS provides the hazard information you need, but a COSHH assessment must consider how the substance is actually used in your workplace. The matching Chemical Risk Assessment (CRA) on this page is a starting point you should adapt to your own tasks and controls.

Safety Data SheetChemical Risk Assessment

Sorafenib

by Cayman Chemical Co.

SDS · PDF, approx. 220 KB CRA · PDF, approx. 180 KB

Sorafenib is supplied by Cayman Chemical Co. under product code 10009644. This page provides both the Safety Data Sheet (SDS) and the Chemical Risk Assessment (CRA) for this substance, under OSHA regulations for UK workplace use under COSHH. The full SDS and CRA documents are available to download above.

This SDS was last revised on 24 October 2025. The matching CRA is updated in line with SDS revisions. Workplaces handling this substance should retain a current SDS and risk assessment for the duration of use.

Language: English
Regulation: OSHA
Revision Date: 24 Oct 2025
Signal Word: DANGER
Product Code: 10009644
CAS Number: 284461-73-0

Switch between the Safety Data Sheet and the Chemical Risk Assessment for this substance.

Hazards at a GlanceFrom the Safety Data Sheet

Signal Word: DANGER

GHS08Health hazard

GHS09Environment

Hazard Statements (H-phrases)

H351: Suspected of causing cancer.
H360: May damage fertility or the unborn child.
H362: May cause harm to breast-fed children.
H372: Causes damage to organs through prolonged or repeated exposure.
H400: Very toxic to aquatic life.
H410: Very toxic to aquatic life with long lasting effects.

Need the full hazard breakdown? Precautionary statements, first aid, physical properties and exposure controls are in the full SDS PDF.

Common QuestionsAbout this Safety Data Sheet

Chemical Risk Assessment SummaryFrom the Chemical Risk Assessment

Assessment Summary

This Chemical Risk Assessment is derived from the Safety Data Sheet for Sorafenib issued by Cayman Chemical Co. on 24 October 2025 It presents the substance's hazards organised by risk level, with the relevant regulatory statements and recommended controls for each. These hazards are rated across two levels: High and Medium Risk, based on the hazard classifications in the SDS.

Hazard PreviewA snapshot of substance hazards and controls

Rating Before Controls

HIGH RISK

H360: May damage fertility or the unborn child

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and un-derstood.

P281 Use personal protective equipment as required.

P405 Store locked up

P501 Dispose of contents/container to correct disposal area.

P308 + P313 IF exposed or concerned: Get medical advice/attention.

Rating Before Controls

HIGH RISK

H351: Suspected of causing cancer

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and un-derstood.

P281 Use personal protective equipment as required

P501 Dispose of contents/container to correct disposal area.

P405 Store locked up

P308 + P313 IF exposed or concerned: Get medical advice/attention.

Rating Before Controls

HIGH RISK

H362: May cause harm to breast-fed children

P203:  Obtain, read and follow all safety instructions before use

P260: Do not breathe dust/fume/gas/mist/vapours/spray.

P263: Avoid contact during pregnancy/while nursing

P270: Do not eat, drink or smoke when using this product

P262: Do not get in eyes, on skin, or on clothing.

P308:  IF exposed or concerned: Get medical advice/attention

Note: This is a preview of the substance's hazards. A substance commonly carries more hazards. Download the full Chemical Risk Assessment for more information.

Recommended Control MeasuresKey PPE and handling controls

Need to download the Chemical Risk Assessment? The full CRA PDF includes all hazard classifications, regulatory statements and recommended controls.

Common QuestionsAbout this Risk Assessment

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Sorafenib

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