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Safety Data Sheet Chemical Risk Assessment

Guanidine Thiocyanate, Molecular Biology Grade

by Avocado Research Chemicals Ltd. (Part of Thermo Fisher Scientific)

SDS · PDF, approx. 220 KB CRA · PDF, approx. 180 KB

Guanidine thiocyanate, Molecular Biology Grade is supplied by Avocado Research Chemicals Ltd. (Part of Thermo Fisher Scientific) under product code J65104. This page provides both the Safety Data Sheet (SDS) and the Chemical Risk Assessment (CRA) for this substance, under GHS/CLP regulations for UK workplace use under COSHH. The full SDS and CRA documents are available to download above.

This SDS was last revised on 14 January 2025. The matching CRA is updated in line with SDS revisions. Workplaces handling this substance should retain a current SDS and risk assessment for the duration of use.

Language
English
Regulation
GHS/CLP
Revision Date
14 Jan 2025
Signal Word
DANGER
Product Code
J65104
CAS Number
593-84-0

Switch between the Safety Data Sheet and the Chemical Risk Assessment for this substance.

Hazards at a Glance From the Safety Data Sheet
Signal Word: DANGER
Harmful / irritant GHS07 Harmful / irritant
Corrosive GHS05 Corrosive
Environment GHS09 Environment
Hazard Statements (H-phrases)
H302
Harmful if swallowed.
H312
Harmful in contact with skin.
H332
Harmful if inhaled.
H314
Causes severe skin burns and eye damage.
H412
Harmful to aquatic life with long lasting effects.
EUH032
Contact with acids liberates very toxic gas.
EUH071
Corrosive to the respiratory tract.

Need the full hazard breakdown? Precautionary statements, first aid, physical properties and exposure controls are in the full SDS PDF.

Download SDS
Common Questions About this Safety Data Sheet
This Safety Data Sheet was issued by Avocado Research Chemicals Ltd. (Part of Thermo Fisher Scientific) on 14 January 2025 under GHS/CLP. ISDSS syncs its database regularly to keep documents current.
Yes, a free ISDSS account is required to download the PDF. Registration takes under two minutes and gives you access to over 1.5 million Safety Data Sheets. Once registered, you can also save documents to your personal library for quick access.
The manufacturer, importer or supplier that places the substance on the market is responsible for providing a current Safety Data Sheet to downstream users, free of charge.
No. An SDS provides the hazard information you need, but a COSHH assessment must consider how the substance is actually used in your workplace. The matching Chemical Risk Assessment (CRA) on this page is a starting point you should adapt to your own tasks and controls.
Chemical Risk Assessment Summary From the Chemical Risk Assessment
Assessment Summary
This Chemical Risk Assessment is derived from the Safety Data Sheet for Guanidine Thiocyanate, Molecular Biology Grade issued by Avocado Research Chemicals Ltd. (part Of Thermo Fisher Scientific) on 14 January 2025 It presents the substance's hazards organised by risk level, with the relevant regulatory statements and recommended controls for each. These hazards are rated across two levels: High and Medium Risk, based on the hazard classifications in the SDS.
Hazard Preview A snapshot of substance hazards and controls
Rating Before Controls
HIGH RISK
H314: Causes severe skin burns and eye damage
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash skin thoroughly after handling.
P501 Dispose of contents/container to correct disposal area.
P405 Store locked up
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P363 Wash contaminated clothing before reuse.
5 other controls in place
Rating Before Controls
HIGH RISK
H312: Harmful in contact with skin
P501 Dispose of contents/container to correct disposal area.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302 + P352 IF ON SKIN: wash with plenty of soap and water
P312 Call a POISON CENTER or doctor/physician if you feel unwell
P322 Specific measures (see …on this label)
P363 Wash contaminated clothing before reuse.
Rating Before Controls
HIGH RISK
H412: Harmful to aquatic life with long lasting effects
P501 Dispose of contents/container to correct disposal area
P273 Avoid release to the environment.
Note: This is a preview of the substance's hazards. A substance commonly carries more hazards. Download the full Chemical Risk Assessment for more information.
Recommended Control Measures Key PPE and handling controls

Need to download the Chemical Risk Assessment? The full CRA PDF includes all hazard classifications, regulatory statements and recommended controls.

Download CRA
Common Questions About this Risk Assessment
This Chemical Risk Assessment provides the substance-level hazard inputs needed for a COSHH assessment under the UK Control of Substances Hazardous to Health Regulations 2002. It is not a substitute for a full workplace risk assessment. You must combine this with your own assessment of how the substance is actually used on your site, including task specifics, exposure duration and local controls.
The CRA is derived from the hazard data in the manufacturer's SDS for Guanidine Thiocyanate, Molecular Biology Grade, mapped against standard workplace task profiles. It is updated in line with SDS revisions. The CRA is a starting point for your own assessment, not a finished document.
A Safety Data Sheet is produced by the manufacturer and describes the hazards of the substance itself. A Chemical Risk Assessment evaluates those hazards in the context of how the substance is actually used in the workplace, covering specific tasks, exposure routes and recommended controls. Both documents work together.
Yes, a free ISDSS account gives you access to both the SDS and the linked CRA for over 1.5 million substances. Registration takes under two minutes.
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