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This Safety Data Sheet was issued by Merck Life Science UK Limited on 18 April 2021 under GHS/CLP. ISDSS syncs its database regularly to keep documents current.

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Can I use this SDS as my COSHH risk assessment?

No. An SDS provides the hazard information you need, but a COSHH assessment must consider how the substance is actually used in your workplace. The matching Chemical Risk Assessment (CRA) on this page is a starting point you should adapt to your own tasks and controls.

Safety Data SheetChemical Risk Assessment

(−)-Nicotine

by Merck Life Science UK Limited

SDS · PDF, approx. 220 KB CRA · PDF, approx. 180 KB

(−)-Nicotine is supplied by Merck Life Science UK Limited under product code N3876. This page provides both the Safety Data Sheet (SDS) and the Chemical Risk Assessment (CRA) for this substance, under GHS/CLP regulations for UK workplace use under COSHH. The full SDS and CRA documents are available to download above.

This SDS was last revised on 18 April 2021. The matching CRA is updated in line with SDS revisions. Workplaces handling this substance should retain a current SDS and risk assessment for the duration of use.

Language: English
Regulation: GHS/CLP
Revision Date: 18 Apr 2021
Signal Word: DANGER
Product Code: N3876
CAS Number: 54-11-5

Switch between the Safety Data Sheet and the Chemical Risk Assessment for this substance.

Hazards at a GlanceFrom the Safety Data Sheet

Signal Word: DANGER

GHS06Acute toxicity

GHS07Harmful / irritant

GHS05Corrosive

GHS09Environment

Hazard Statements (H-phrases)

H300: Fatal if swallowed.
H310: Fatal in contact with skin.
H330: Fatal if inhaled.
H315: Causes skin irritation.
H318: Causes serious eye damage.
H411: Toxic to aquatic life with long lasting effects.

Need the full hazard breakdown? Precautionary statements, first aid, physical properties and exposure controls are in the full SDS PDF.

Common QuestionsAbout this Safety Data Sheet

Chemical Risk Assessment SummaryFrom the Chemical Risk Assessment

Assessment Summary

This Chemical Risk Assessment is derived from the Safety Data Sheet for (−)-Nicotine issued by Merck Life Science Uk Limited on 18 April 2021 It presents the substance's hazards organised by risk level, with the relevant regulatory statements and recommended controls for each. These hazards are rated across two levels: High and Low Risk, based on the hazard classifications in the SDS.

Hazard PreviewA snapshot of substance hazards and controls

Rating Before Controls

HIGH RISK

H300: Fatal if swallowed

P264 Wash skin thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P501 Dispose of contents/container to correct disposal area.

P405 Store locked up

P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321 Specific treatment (see … on this label)

1 other control in place

Rating Before Controls

HIGH RISK

H310: Fatal in contact with skin

P262 Do not get in eyes, on skin, or on clothing

P264 Wash skin thoroughly after handling.

P270 Do not eat, drink or smoke when using this product

P405 Store locked up

P501 Dispose of contents/container to correct disposal area

P280: Wear protective gloves/protective clothing/eye protection/face protection.

5 other controls in place

Rating Before Controls

HIGH RISK

H330: Fatal if inhaled

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P284 Wear respiratory protection.

P233 Keep container tightly closed.

P403 + P233 Store in a well-ventilated place. Keep container tightly closed.

P501 Dispose of contents/container to correct disposal area.

4 other controls in place

Note: This is a preview of the substance's hazards. A substance commonly carries more hazards. Download the full Chemical Risk Assessment for more information.

Recommended Control MeasuresKey PPE and handling controls

Need to download the Chemical Risk Assessment? The full CRA PDF includes all hazard classifications, regulatory statements and recommended controls.

Common QuestionsAbout this Risk Assessment

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(−)-Nicotine

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