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This Safety Data Sheet was issued by LGC GmbH on 21 October 2021 under GHS/CLP. ISDSS syncs its database regularly to keep documents current.

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Can I use this SDS as my COSHH risk assessment?

No. An SDS provides the hazard information you need, but a COSHH assessment must consider how the substance is actually used in your workplace. The matching Chemical Risk Assessment (CRA) on this page is a starting point you should adapt to your own tasks and controls.

Safety Data SheetChemical Risk Assessment

Methotrexate-D3

by LGC GmbH

SDS · PDF, approx. 220 KB CRA · PDF, approx. 180 KB

Methotrexate-D3 is supplied by LGC GmbH under product code TRC-M260677-10MG. This page provides both the Safety Data Sheet (SDS) and the Chemical Risk Assessment (CRA) for this substance, under GHS/CLP regulations for UK workplace use under COSHH. The full SDS and CRA documents are available to download above.

This SDS was last revised on 21 October 2021. The matching CRA is updated in line with SDS revisions. Workplaces handling this substance should retain a current SDS and risk assessment for the duration of use.

Language: Greek
Regulation: GHS/CLP
Revision Date: 21 Oct 2021
Signal Word: DANGER
Product Code: TRC-M260677-10MG
CAS Number: 432545-63-6

Switch between the Safety Data Sheet and the Chemical Risk Assessment for this substance.

Hazards at a GlanceFrom the Safety Data Sheet

Signal Word: DANGER

GHS06Acute toxicity

GHS08Health hazard

Hazard Statements (H-phrases)

H301: Toxic if swallowed.
H311: Toxic in contact with skin.
H331: Toxic if inhaled.
H340: May cause genetic defects.
H360DF: See full Safety Data Sheet for the hazard statement wording.
H372: Causes damage to organs through prolonged or repeated exposure.

Need the full hazard breakdown? Precautionary statements, first aid, physical properties and exposure controls are in the full SDS PDF.

Common QuestionsAbout this Safety Data Sheet

Chemical Risk Assessment SummaryFrom the Chemical Risk Assessment

Assessment Summary

This Chemical Risk Assessment is derived from the Safety Data Sheet for Methotrexate-D3 issued by Lgc Gmbh on 21 October 2021 It presents the substance's hazards organised by risk level, with the relevant regulatory statements and recommended controls for each. These hazards are rated across one level: High Risk, based on the hazard classifications in the SDS.

Hazard PreviewA snapshot of substance hazards and controls

Rating Before Controls

HIGH RISK

H340: May cause genetic defects

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and un-derstood

P281 Use personal protective equipment as required

P501 Dispose of contents/container to correct disposal area.

P405 Store locked up.

P308 + P313 IF exposed or concerned: Get medical advice/attention.

Rating Before Controls

HIGH RISK

H301: Toxic if swallowed

P264 Wash skin thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P501 Dispose of contents/container to correct disposal area.

P405 Store locked up

P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321 Specific treatment (see … on this label)

1 other control in place

Rating Before Controls

HIGH RISK

H311: Toxic in contact with skin

P501 Dispose of contents/container to correct disposal area.

P405 Store locked up

P280: Wear protective gloves/protective clothing/eye protection/face protection.

<p>P302 + P352 IF ON SKIN: wash with plenty of soap and water.</p>

P312 Call a POISON CENTER or doctor/physician if you feel unwell

P322 Specific measures (see …on this label)

2 other controls in place

Note: This is a preview of the substance's hazards. A substance commonly carries more hazards. Download the full Chemical Risk Assessment for more information.

Recommended Control MeasuresKey PPE and handling controls

Need to download the Chemical Risk Assessment? The full CRA PDF includes all hazard classifications, regulatory statements and recommended controls.

Common QuestionsAbout this Risk Assessment

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Methotrexate-D3

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