Safety Data SheetChemical Risk Assessment
Fluorouracil, Usp
by Spectrum Chemical Mfg. Corp
SDS · PDF, approx. 220 KB CRA · PDF, approx. 180 KB
Fluorouracil, Usp is supplied by Spectrum Chemical Mfg. Corp under product code FL127. This page provides both the Safety Data Sheet (SDS) and the Chemical Risk Assessment (CRA) for this substance, under OSHA regulations for UK workplace use under COSHH. The full SDS and CRA documents are available to download above.
This SDS was last revised on 20 June 2018. The matching CRA is updated in line with SDS revisions. Workplaces handling this substance should retain a current SDS and risk assessment for the duration of use.
- Language
- English
- Regulation
- OSHA
- Revision Date
- 20 Jun 2018
- Signal Word
- DANGER
- Product Code
- FL127
- CAS Number
- 51-21-8
Switch between the Safety Data Sheet and the Chemical Risk Assessment for this substance.
Hazards at a GlanceFrom the Safety Data Sheet
Signal Word: DANGER
GHS06Acute toxicity
GHS07Harmful / irritant
GHS08Health hazardHazard Statements (H-phrases)
- H301
- Toxic if swallowed.
- H315
- Causes skin irritation.
- H319
- Causes serious eye irritation.
- H340
- May cause genetic defects.
- H360
- May damage fertility or the unborn child.
Need the full hazard breakdown? Precautionary statements, first aid, physical properties and exposure controls are in the full SDS PDF.
Common QuestionsAbout this Safety Data Sheet
This Safety Data Sheet was issued by Spectrum Chemical Mfg. Corp on 20 June 2018 under OSHA. ISDSS syncs its database regularly to keep documents current.
Yes, a free ISDSS account is required to download the PDF. Registration takes under two minutes and gives you access to over 1.5 million Safety Data Sheets. Once registered, you can also save documents to your personal library for quick access.
The manufacturer, importer or supplier that places the substance on the market is responsible for providing a current Safety Data Sheet to downstream users, free of charge.
No. An SDS provides the hazard information you need, but a COSHH assessment must consider how the substance is actually used in your workplace. The matching Chemical Risk Assessment (CRA) on this page is a starting point you should adapt to your own tasks and controls.
Chemical Risk Assessment SummaryFrom the Chemical Risk Assessment
Assessment Summary
This Chemical Risk Assessment is derived from the Safety Data Sheet for Fluorouracil, Usp issued by Spectrum Chemical Mfg. Corp on 20 June 2018 It presents the substance's hazards organised by risk level, with the relevant regulatory statements and recommended controls for each. These hazards are rated across two levels: High and Low Risk, based on the hazard classifications in the SDS.
Hazard PreviewA snapshot of substance hazards and controls
Rating Before Controls
HIGH RISK
H340: May cause genetic defects
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and un-derstood
P281 Use personal protective equipment as required
P501 Dispose of contents/container to correct disposal area.
P405 Store locked up.
P308 + P313 IF exposed or concerned: Get medical advice/attention.
Rating Before Controls
HIGH RISK
H360: May damage fertility or the unborn child
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and un-derstood.
P281 Use personal protective equipment as required.
P405 Store locked up
P501 Dispose of contents/container to correct disposal area.
P308 + P313 IF exposed or concerned: Get medical advice/attention.
Rating Before Controls
HIGH RISK
H301: Toxic if swallowed
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P501 Dispose of contents/container to correct disposal area.
P405 Store locked up
P301 + P310
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label)
1 other control in place
Note: This is a preview of the substance's hazards. A substance commonly carries more hazards. Download the full Chemical Risk Assessment for more information.
Recommended Control MeasuresKey PPE and handling controls
Need to download the Chemical Risk Assessment? The full CRA PDF includes all hazard classifications, regulatory statements and recommended controls.
Common QuestionsAbout this Risk Assessment
This Chemical Risk Assessment provides the substance-level hazard inputs needed for a COSHH assessment under the UK Control of Substances Hazardous to Health Regulations 2002. It is not a substitute for a full workplace risk assessment. You must combine this with your own assessment of how the substance is actually used on your site, including task specifics, exposure duration and local controls.
The CRA is derived from the hazard data in the manufacturer's SDS for Fluorouracil, Usp, mapped against standard workplace task profiles. It is updated in line with SDS revisions. The CRA is a starting point for your own assessment, not a finished document.
A Safety Data Sheet is produced by the manufacturer and describes the hazards of the substance itself. A Chemical Risk Assessment evaluates those hazards in the context of how the substance is actually used in the workplace, covering specific tasks, exposure routes and recommended controls. Both documents work together.
Yes, a free ISDSS account gives you access to both the SDS and the linked CRA for over 1.5 million substances. Registration takes under two minutes.