Safety Data SheetChemical Risk Assessment
Dithiothreitol, Thermo Scientific
by Avocado Research Chemicals Ltd.
SDS · PDF, approx. 220 KB CRA · PDF, approx. 180 KB
Dithiothreitol, Thermo Scientific is supplied by Avocado Research Chemicals Ltd. under product code J15395. This page provides both the Safety Data Sheet (SDS) and the Chemical Risk Assessment (CRA) for this substance, under GHS/CLP regulations for UK workplace use under COSHH. The full SDS and CRA documents are available to download above.
This SDS was last revised on 2 February 2024. The matching CRA is updated in line with SDS revisions. Workplaces handling this substance should retain a current SDS and risk assessment for the duration of use.
- Language
- English
- Regulation
- GHS/CLP
- Revision Date
- 02 Feb 2024
- Signal Word
- WARNING
- Product Code
- J15395
- CAS Number
- 3483-12-3
Switch between the Safety Data Sheet and the Chemical Risk Assessment for this substance.
Hazards at a GlanceFrom the Safety Data Sheet
Signal Word: WARNING
GHS07Harmful / irritantHazard Statements (H-phrases)
- H302
- Harmful if swallowed.
- H315
- Causes skin irritation.
- H319
- Causes serious eye irritation.
- H335
- May cause respiratory irritation.
Need the full hazard breakdown? Precautionary statements, first aid, physical properties and exposure controls are in the full SDS PDF.
Common QuestionsAbout this Safety Data Sheet
This Safety Data Sheet was issued by Avocado Research Chemicals Ltd. on 2 February 2024 under GHS/CLP. ISDSS syncs its database regularly to keep documents current.
Yes, a free ISDSS account is required to download the PDF. Registration takes under two minutes and gives you access to over 1.5 million Safety Data Sheets. Once registered, you can also save documents to your personal library for quick access.
The manufacturer, importer or supplier that places the substance on the market is responsible for providing a current Safety Data Sheet to downstream users, free of charge.
No. An SDS provides the hazard information you need, but a COSHH assessment must consider how the substance is actually used in your workplace. The matching Chemical Risk Assessment (CRA) on this page is a starting point you should adapt to your own tasks and controls.
Chemical Risk Assessment SummaryFrom the Chemical Risk Assessment
Assessment Summary
This Chemical Risk Assessment is derived from the Safety Data Sheet for Dithiothreitol, Thermo Scientific issued by Avocado Research Chemicals Ltd. on 2 February 2024 It presents the substance's hazards organised by risk level, with the relevant regulatory statements and recommended controls for each. These hazards are rated across three levels: High, Medium and Low Risk, based on the hazard classifications in the SDS.
Hazard PreviewA snapshot of substance hazards and controls
Rating Before Controls
HIGH RISK
H319: Causes serious eye irritation
P264 Wash skin thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P305 + P351 + P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P313 + P337 If eye irritation persists Get medical advice/attention
Rating Before Controls
MEDIUM RISK
H302: Harmful if swallowed
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product
P501 Dispose of contents/container to correct disposal area.
P330 Rinse mouth
P301 + P312
IF SWALLOWED: call a POISON CENTER or doctor/physician IF you
feel unwel
Rating Before Controls
LOW RISK
H315: Causes skin irritation
P264 Wash skin thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P362 Take off contaminated clothing and wash before reuse.
P302 + P352 IF ON SKIN: wash with plenty of soap and water
P321 Specific treatment (see … on this label)
P332 + P313 IF SKIN irritation occurs: Get medical advice/attention.
Note: This is a preview of the substance's hazards. A substance commonly carries more hazards. Download the full Chemical Risk Assessment for more information.
Recommended Control MeasuresKey PPE and handling controls
Need to download the Chemical Risk Assessment? The full CRA PDF includes all hazard classifications, regulatory statements and recommended controls.
Common QuestionsAbout this Risk Assessment
This Chemical Risk Assessment provides the substance-level hazard inputs needed for a COSHH assessment under the UK Control of Substances Hazardous to Health Regulations 2002. It is not a substitute for a full workplace risk assessment. You must combine this with your own assessment of how the substance is actually used on your site, including task specifics, exposure duration and local controls.
The CRA is derived from the hazard data in the manufacturer's SDS for Dithiothreitol, Thermo Scientific, mapped against standard workplace task profiles. It is updated in line with SDS revisions. The CRA is a starting point for your own assessment, not a finished document.
A Safety Data Sheet is produced by the manufacturer and describes the hazards of the substance itself. A Chemical Risk Assessment evaluates those hazards in the context of how the substance is actually used in the workplace, covering specific tasks, exposure routes and recommended controls. Both documents work together.
Yes, a free ISDSS account gives you access to both the SDS and the linked CRA for over 1.5 million substances. Registration takes under two minutes.