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This Safety Data Sheet was issued by Pfizer Ltd on 8 February 2018 under OSHA. ISDSS syncs its database regularly to keep documents current.

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Can I use this SDS as my COSHH risk assessment?

No. An SDS provides the hazard information you need, but a COSHH assessment must consider how the substance is actually used in your workplace. The matching Chemical Risk Assessment (CRA) on this page is a starting point you should adapt to your own tasks and controls.

Safety Data SheetChemical Risk Assessment

Crizotinib Capsules

by Pfizer Ltd

SDS · PDF, approx. 220 KB CRA · PDF, approx. 180 KB

Crizotinib Capsules is supplied by Pfizer Ltd under product code XALKORI, CRIZALK. This page provides both the Safety Data Sheet (SDS) and the Chemical Risk Assessment (CRA) for this substance, under OSHA regulations for UK workplace use under COSHH. The full SDS and CRA documents are available to download above.

This SDS was last revised on 8 February 2018. The matching CRA is updated in line with SDS revisions. Workplaces handling this substance should retain a current SDS and risk assessment for the duration of use.

Language: English
Regulation: OSHA
Revision Date: 08 Feb 2018
Signal Word: DANGER
Product Code: XALKORI, CRIZALK
CAS Number: 877399-52-5,7757-93-9,9004-34-6,557-04-0,1309-37-1,13463-67-7,9063-38-1,9000-70-8

Switch between the Safety Data Sheet and the Chemical Risk Assessment for this substance.

Hazards at a GlanceFrom the Safety Data Sheet

Signal Word: DANGER

GHS08Health hazard

GHS07Harmful / irritant

GHS09Environment

GHS05Corrosive

Hazard Statements (H-phrases)

H318: Causes serious eye damage.
H317: May cause an allergic skin reaction.
H341: Suspected of causing genetic defects.
H400: Very toxic to aquatic life.

Need the full hazard breakdown? Precautionary statements, first aid, physical properties and exposure controls are in the full SDS PDF.

Common QuestionsAbout this Safety Data Sheet

Chemical Risk Assessment SummaryFrom the Chemical Risk Assessment

Assessment Summary

This Chemical Risk Assessment is derived from the Safety Data Sheet for Crizotinib Capsules issued by Pfizer Ltd on 8 February 2018 It presents the substance's hazards organised by risk level, with the relevant regulatory statements and recommended controls for each. These hazards are rated across three levels: High, Medium and Low Risk, based on the hazard classifications in the SDS.

Hazard PreviewA snapshot of substance hazards and controls

Rating Before Controls

HIGH RISK

H318: Causes serious eye damage

P280: Wear protective gloves/protective clothing/eye protection/face protection.

P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P310 Immediately call a POISON CENTER or doctor/physician

Rating Before Controls

HIGH RISK

H341: Suspected of causing genetic defects

P201 Obtain special instructions before use

P202 Do not handle until all safety precautions have been read and un-derstood

P281 Use personal protective equipment as required.

P405 Store locked up.

P501 Dispose of contents/container to correct disposal area.

P308 + P313 IF exposed or concerned: Get medical advice/attention.

Rating Before Controls

MEDIUM RISK

H400: Very toxic to aquatic life

Don't pour down drains

P273 Avoid release to the environment

P501 Dispose of contents/container to correct disposal area

P391 Collect spillage. Hazardous to the aquatic environment

Note: This is a preview of the substance's hazards. A substance commonly carries more hazards. Download the full Chemical Risk Assessment for more information.

Recommended Control MeasuresKey PPE and handling controls

Need to download the Chemical Risk Assessment? The full CRA PDF includes all hazard classifications, regulatory statements and recommended controls.

Common QuestionsAbout this Risk Assessment

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Crizotinib Capsules

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