Safety Data SheetChemical Risk Assessment
Acetonitrile 50% / Water 47.5% / Trifluoroacetic Acid 2.5% HiPerSolv Chromanorm Solution Os (Bruker Organic Solvent)
by VWR International Ltd.
SDS · PDF, approx. 220 KB CRA · PDF, approx. 180 KB
Acetonitrile 50% / Water 47.5% / Trifluoroacetic Acid 2.5% HiPerSolv Chromanorm Solution Os (Bruker Organic Solvent) is supplied by VWR International Ltd. under product code 89449. This page provides both the Safety Data Sheet (SDS) and the Chemical Risk Assessment (CRA) for this substance, under GHS/CLP regulations for UK workplace use under COSHH. The full SDS and CRA documents are available to download above.
This SDS was last revised on 7 July 2021. The matching CRA is updated in line with SDS revisions. Workplaces handling this substance should retain a current SDS and risk assessment for the duration of use.
- Language
- English
- Regulation
- GHS/CLP
- Revision Date
- 07 Jul 2021
- Signal Word
- DANGER
- Product Code
- 89449
- CAS Number
- 75-05-8,76-05-1
Switch between the Safety Data Sheet and the Chemical Risk Assessment for this substance.
Hazards at a GlanceFrom the Safety Data Sheet
Signal Word: DANGER
GHS02Flammable
GHS05Corrosive
GHS07Harmful / irritantHazard Statements (H-phrases)
- H225
- Highly flammable liquid and vapour.
- H290
- May be corrosive to metals.
- H315
- Causes skin irritation.
- H318
- Causes serious eye damage.
- H302+H312+H332
- See full Safety Data Sheet for the hazard statement wording.
Need the full hazard breakdown? Precautionary statements, first aid, physical properties and exposure controls are in the full SDS PDF.
Common QuestionsAbout this Safety Data Sheet
This Safety Data Sheet was issued by VWR International Ltd. on 7 July 2021 under GHS/CLP. ISDSS syncs its database regularly to keep documents current.
Yes, a free ISDSS account is required to download the PDF. Registration takes under two minutes and gives you access to over 1.5 million Safety Data Sheets. Once registered, you can also save documents to your personal library for quick access.
The manufacturer, importer or supplier that places the substance on the market is responsible for providing a current Safety Data Sheet to downstream users, free of charge.
No. An SDS provides the hazard information you need, but a COSHH assessment must consider how the substance is actually used in your workplace. The matching Chemical Risk Assessment (CRA) on this page is a starting point you should adapt to your own tasks and controls.
Chemical Risk Assessment SummaryFrom the Chemical Risk Assessment
Assessment Summary
This Chemical Risk Assessment is derived from the Safety Data Sheet for Acetonitrile 50% / Water 47.5% / Trifluoroacetic Acid 2.5% HiPerSolv Chromanorm Solution Os (Bruker Organic Solvent) issued by Vwr International Ltd. on 7 July 2021 It presents the substance's hazards organised by risk level, with the relevant regulatory statements and recommended controls for each. These hazards are rated across two levels: High and Low Risk, based on the hazard classifications in the SDS.
Hazard PreviewA snapshot of substance hazards and controls
Rating Before Controls
HIGH RISK
H318: Causes serious eye damage
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P305 + P351 + P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER or doctor/physician
Rating Before Controls
HIGH RISK
H225: Highly flammable liquid and vapour
210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking
P242 Use only non-sparking tools.
P240 Ground/bond container and receiving equipment
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment
P243 Take precautionary measures against static discharge
P235 Keep cool.
5 other controls in place
Rating Before Controls
HIGH RISK
H290: May be corrosive to metals
P234 Keep only in original container
P406 Store in corrosive resistant/… container with a resistant inner liner
P390 Absorb spillage to prevent material damage.
Note: This is a preview of the substance's hazards. A substance commonly carries more hazards. Download the full Chemical Risk Assessment for more information.
Recommended Control MeasuresKey PPE and handling controls
Need to download the Chemical Risk Assessment? The full CRA PDF includes all hazard classifications, regulatory statements and recommended controls.
Common QuestionsAbout this Risk Assessment
This Chemical Risk Assessment provides the substance-level hazard inputs needed for a COSHH assessment under the UK Control of Substances Hazardous to Health Regulations 2002. It is not a substitute for a full workplace risk assessment. You must combine this with your own assessment of how the substance is actually used on your site, including task specifics, exposure duration and local controls.
The CRA is derived from the hazard data in the manufacturer's SDS for Acetonitrile 50% / Water 47.5% / Trifluoroacetic Acid 2.5% HiPerSolv Chromanorm Solution Os (Bruker Organic Solvent), mapped against standard workplace task profiles. It is updated in line with SDS revisions. The CRA is a starting point for your own assessment, not a finished document.
A Safety Data Sheet is produced by the manufacturer and describes the hazards of the substance itself. A Chemical Risk Assessment evaluates those hazards in the context of how the substance is actually used in the workplace, covering specific tasks, exposure routes and recommended controls. Both documents work together.
Yes, a free ISDSS account gives you access to both the SDS and the linked CRA for over 1.5 million substances. Registration takes under two minutes.